NR1H4 antibody (AA 1-476) (HRP)
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- Target See all NR1H4 Antibodies
- NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
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Binding Specificity
- AA 1-476
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR1H4 antibody is conjugated to HRP
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Bile acid receptor protein (1-476AA)
- Isotype
- IgG
- Top Product
- Discover our top product NR1H4 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
- Alternative Name
- NR1H4 (NR1H4 Products)
- Synonyms
- zgc:110190 antibody, zgc:92742 antibody, NR1H4 antibody, BAR antibody, FXR antibody, HRR-1 antibody, HRR1 antibody, RIP14 antibody, AI957360 antibody, Fxr antibody, Rxrip14 antibody, nuclear receptor subfamily 1, group H, member 5 S homeolog antibody, nuclear receptor subfamily 1, group H, member 4 antibody, nuclear receptor subfamily 1 group H member 4 antibody, nr1h5.S antibody, nr1h4 antibody, NR1H4 antibody, Nr1h4 antibody
- Background
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Background: Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.
Aliases: BAR antibody, Bile acid receptor antibody, Farnesoid X activated receptor antibody, Farnesoid X receptor antibody, Farnesoid X-activated receptor antibody, Farnesol receptor HRR 1 antibody, Farnesol receptor HRR-1 antibody, Farnesol receptor HRR1 antibody, FXR antibody, HRR 1 antibody, HRR1 antibody, NR1H4 antibody, NR1H4_HUMAN antibody, Nuclear receptor subfamily 1 group H member 4 antibody, Retinoid X receptor interacting protein 14 antibody, Retinoid X receptor-interacting protein 14 antibody, RIP 14 antibody, RIP14 antibody, RXR interacting protein 14 antibody, RXR-interacting protein 14 antibody
- UniProt
- Q96RI1
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Carbohydrate Metabolic Process
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