BACE1 antibody (AA 46-155)

Catalog No. ABIN7145531

Product Details anti-BACE1 Antibody

Target: BACE1 (Beta-secretase 1 (BACE1))

Binding Specificity: AA 46-155

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACE1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Beta-secretase 1 protein (46-155AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BACE1

Target: BACE1 (Beta-secretase 1 (BACE1))

Alternative Name: BACE1 (BACE1 Products)

Synonyms: ASP2 antibody, BACE antibody, HSPC104 antibody, C76936 antibody, Bace antibody, MGC145931 antibody, BACE1 antibody, zgc:77409 antibody, beta-secretase 1 antibody, beta-site APP cleaving enzyme 1 antibody, beta-site APP-cleaving enzyme 1 antibody, BACE1 antibody, Bace1 antibody, bace1 antibody

Background:

Background: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

Aliases: APP beta secretase antibody, Asp 2 antibody, ASP2 antibody, Aspartyl protease 2 antibody, BACE 1 antibody, BACE antibody, BACE1 antibody, BACE1_HUMAN antibody, Beta secretase 1 antibody, Beta secretase antibody, Beta site amyloid beta A4 precursor protein cleaving enzyme antibody, Beta site amyloid precursor protein cleaving enzyme 1 antibody, Beta site amyloid precursor protein cleaving enzyme antibody, Beta site APP cleaving enzyme 1 antibody, Beta site APP cleaving enzyme antibody, Beta-secretase 1 antibody, Beta-site amyloid precursor protein cleaving enzyme 1 antibody, Beta-site APP cleaving enzyme 1 antibody, FLJ90568 antibody, HSPC104 antibody, Memapsin 2 antibody, Memapsin-2 antibody, Memapsin2 antibody, Membrane associated aspartic protease 2 antibody, Membrane-associated aspartic protease 2 antibody, Transmembrane aspartic proteinase Asp2 antibody

UniProt: P56817