BATF2 antibody (AA 1-189) (Biotin)
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- Target See all BATF2 products
- BATF2 (Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))
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Binding Specificity
- AA 1-189
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BATF2 antibody is conjugated to Biotin
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Basic leucine zipper transcriptional factor ATF-like 2 protein (1-189AA)
- Isotype
- IgG
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- BATF2 (Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))
- Alternative Name
- BATF2 (BATF2 Products)
- Synonyms
- RGD1311481 antibody, BATF2 antibody, SARI antibody, 4933430F08Rik antibody, basic leucine zipper ATF-like transcription factor 2 antibody, basic leucine zipper transcription factor, ATF-like 2 antibody, Batf2 antibody, BATF2 antibody
- Background
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Background: AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5\'-TGA[CG]TCA-3\' and regulates expression of target genes. Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.
Aliases: BATF2Basic leucine zipper transcriptional factor ATF-like 2 antibody, B-ATF-2 antibody, Suppressor of AP-1 regulated by IFN antibody, SARI antibody
- UniProt
- Q8N1L9
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