SUPV3L1 antibody (AA 499-786)

Catalog No. ABIN7145007

Product Details anti-SUPV3L1 Antibody

Target: SUPV3L1 (Suppressor of Var1, 3-Like 1 (SUPV3L1))

Binding Specificity: AA 499-786

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUPV3L1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human ATP-dependent RNA helicase SUPV3L1, mitochondrial protein (499-786AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SUPV3L1

Target: SUPV3L1 (Suppressor of Var1, 3-Like 1 (SUPV3L1))

Alternative Name: SUPV3L1 (SUPV3L1 Products)

Synonyms: SUV3 antibody, 6330443E10Rik antibody, wu:fc19b02 antibody, wu:fe37e06 antibody, Suv3 like RNA helicase antibody, suppressor of var1, 3-like 1 (S. cerevisiae) antibody, SUV3-like helicase antibody, SUPV3L1 antibody, Supv3l1 antibody, supv3l1 antibody

Background:

Background: Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3\' overhang double-stranded RNA with a 3\'-to-5\' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5\'-to-3\' direction. Plays a role in the RNA surveillance system in mitochondria, regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.

Aliases: 6330443E10Rik antibody, ATP dependent RNA helicase SUPV3L1, mitochondrial antibody, ATP-dependent RNA helicase SUPV3L1 antibody, EC 3.6.1. antibody, MGC109049 antibody, mitochondrial antibody, OTTHUMP00000019719 antibody, S. Cerevisiae suppressor of var 1 3 like 1 antibody, suppressor of var1 (S.cerevisiae) 3 like 1 antibody, Suppressor of var1 3 like 1 (S. cerevisiae) antibody, Suppressor of var1 3 like 1 (S. cerevisiae)(SUV3) antibody, Suppressor of var1 3 like 1 antibody, Suppressor of var1 3 like protein 1 antibody, Suppressor of var1 3-like protein 1 antibody, SUPV 3 L 1 antibody, SUPV3L1 antibody, SUV 3 antibody, SUV 3 L 1 antibody, SUV3 antibody, SUV3 like protein 1 antibody, SUV3-like protein 1 antibody, SUV3_HUMAN antibody, SUV3L1 antibody

UniProt: Q8IYB8