ARRDC3 antibody (AA 1-270)

Catalog No. ABIN7144639

Product Details anti-ARRDC3 Antibody

Target: ARRDC3 (Arrestin Domain Containing 3 (ARRDC3))

Binding Specificity: AA 1-270

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARRDC3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Arrestin domain-containing protein 3 protein (1-270AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ARRDC3

Target: ARRDC3 (Arrestin Domain Containing 3 (ARRDC3))

Alternative Name: ARRDC3 (ARRDC3 Products)

Background:

Background: Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors (PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation (PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2 (PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes (PubMed:23208550).

Aliases: ARRDC3 antibody, KIAA1376 antibody, Arrestin domain-containing protein 3 antibody, TBP-2-like inducible membrane protein antibody, TLIMP antibody

UniProt: Q96B67