ARPIN antibody (AA 1-226)

Catalog No. ABIN7144631

Product Details anti-ARPIN Antibody

Target: ARPIN

Binding Specificity: AA 1-226

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARPIN antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Arpin protein (1-226AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ARPIN

Target: ARPIN

Abstract: ARPIN Products

Synonyms: actin-related protein 2/3 complex inhibitor antibody, actin related protein 2/3 complex inhibitor antibody, actin related protein 2/3 complex inhibitor L homeolog antibody, Arpin antibody, ARPIN antibody, arpin.L antibody

Background:

Background: Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence.

Aliases: 2610034B18Rik antibody, Actin related protein 2/3 complex inhibitor antibody, Arp2/3 inhibition protein antibody, ARPIN antibody, C15orf38 antibody, Chromosome 15 open reading frame 38 antibody, CO038_HUMAN antibody, Hypothetical protein LOC348110 antibody, MGC61550 antibody, RIKEN cDNA 2610034B18 antibody, UPF0552 protein C15orf38 antibody

UniProt: Q7Z6K5