GIT1 antibody (AA 470-642)

Catalog No. ABIN7144546

Product Details anti-GIT1 Antibody

Target: GIT1

Binding Specificity: AA 470-642

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human ARF GTPase-activating protein GIT1 protein (470-642AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GIT1

Target: GIT1

Alternative Name: GIT1 (GIT1 Products)

Synonyms: Cat-1 antibody, p95Cat antibody, GIT ArfGAP 1 antibody, G protein-coupled receptor kinase interacting ArfGAP 1 antibody, G protein-coupled receptor kinase-interactor 1 antibody, GIT1 antibody, Git1 antibody

Background:

Background: GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis, the function may involve SDCCAG3 and PTPN13 (By similarity).

Aliases: ARF GAP GIT1 antibody, ARF GTPase activating protein GIT1 antibody, ARF GTPase-activating protein GIT1 antibody, CAT 1 antibody, CAT-1 antibody, CaT1 antibody, Cool associated and tyrosine phosphorylated protein 1 antibody, Cool-associated and tyrosine-phosphorylated protein 1 antibody, G protein coupled receptor kinase interacting ArfGAP 1 antibody, G protein coupled receptor kinase interactor 1 antibody, G protein-coupled receptor kinase-interactor 1 antibody, GIT1 antibody, GIT1_HUMAN antibody, GRK interacting protein 1 antibody, GRK-interacting protein 1 antibody

UniProt: Q9Y2X7