Aprataxin antibody (AA 92-161)

Catalog No. ABIN7144491

Product Details anti-Aprataxin Antibody

Target: Aprataxin (APTX)

Binding Specificity: AA 92-161

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aprataxin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Aprataxin protein (92-161AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Aprataxin

Target: Aprataxin (APTX)

Alternative Name: APTX (APTX Products)

Synonyms: aptx antibody, APTX antibody, LOC100284636 antibody, APRATAXIN-like antibody, T10O8.20 antibody, T10O8_20 antibody, AOA antibody, AOA1 antibody, AXA1 antibody, EAOH antibody, EOAHA antibody, FHA-HIT antibody, 2410016G21Rik antibody, AA388047 antibody, aprataxin antibody, FHA-HIT antibody, APRATAXIN-like protein antibody, aprataxin L homeolog antibody, aptx antibody, APTX antibody, CpipJ_CPIJ001673 antibody, LOC100284636 antibody, aptx.L antibody, Aptx antibody

Background:

Background: DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5\'-phosphate termini, resulting in the production of 5\'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5\'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity.

Aliases: AOA 1 antibody, AOA antibody, AOA1 antibody, Aprataxin antibody, Aprataxin homolog antibody, Aptx antibody, APTX_HUMAN antibody, Ataxia 1 early onset with hypoalbuminemia antibody, Ataxia1 early onset with hypoalbuminemia antibody, AXA 1 antibody, AXA1 antibody, EAOH antibody, EOAHA antibody, FHA HIT antibody, FHA-HIT antibody, FLJ20157 antibody, Forkhead associated domain histidine triad like antibody, Forkhead associated domain histidine triad like protein antibody, Forkhead-associated domain histidine triad-like protein antibody, MGC1072 antibody

UniProt: Q7Z2E3

Pathways: DNA Damage Repair, Chromatin Binding