AEN antibody (AA 117-325) (Biotin)

Catalog No. ABIN7144469

Product Details anti-AEN Antibody (Biotin)

Target: AEN (Apoptosis Enhancing Nuclease (AEN))

Binding Specificity: AA 117-325

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AEN antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Apoptosis-enhancing nuclease protein (117-325AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AEN

Target: AEN (Apoptosis Enhancing Nuclease (AEN))

Alternative Name: AEN (AEN Products)

Synonyms: AEN antibody, ISG20L1 antibody, xaen antibody, isg20l1 antibody, MGC147218 antibody, pp12744 antibody, 2700083B06Rik antibody, Isg20l1 antibody, RGD1305051 antibody, apoptosis enhancing nuclease antibody, apoptosis enhancing nuclease L homeolog antibody, AEN antibody, aen.L antibody, aen antibody, Aen antibody

Background:

Background: Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.

Aliases: Aen antibody, AEN_HUMAN antibody, apoptosis enhancing nuclease antibody, Apoptosis-enhancing nuclease antibody, Interferon stimulated exonuclease gene 20 kDa like 1 antibody, Interferon stimulated exonuclease gene 20 kDa like 1, isoform CRA_a antibody, Interferon-stimulated 20 kDa exonuclease-like 1 antibody, ISG20L1 antibody, pp12744 antibody

UniProt: Q8WTP8