Anoctamin 6 antibody (AA 12-100) (Biotin)

Catalog No. ABIN7144313

Product Details anti-Anoctamin 6 Antibody (Biotin)

Target: Anoctamin 6 (ANO6)

Binding Specificity: AA 12-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Anoctamin 6 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Anoctamin-6 protein (12-100AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Anoctamin 6

Target: Anoctamin 6 (ANO6)

Alternative Name: ANO6 (ANO6 Products)

Synonyms: TMEM16F antibody, 2900059G15Rik antibody, AA407480 antibody, AW554778 antibody, F730003B03Rik antibody, Tmem16f antibody, BDPLT7 antibody, SCTS antibody, anoctamin 6 antibody, ANO6 antibody, ano6 antibody, Ano6 antibody

Background:

Background: Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium-dependent phospholipid scramblase activity, scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes.

Aliases: 2900059G15Rik antibody, AA407480 antibody, Ano6 antibody, ANO6_HUMAN antibody, Anoctamin 6 antibody, Anoctamin-6 antibody, AW554778 antibody, BDPLT7 antibody, F730003B03Rik antibody, MGC104751 antibody, SCTS antibody, TMEM16F antibody, Transmembrane protein 16F antibody

UniProt: Q4KMQ2

Pathways: SARS-CoV-2 Protein Interactome