ANGPTL4 antibody (AA 26-406)

Catalog No. ABIN7144121

Product Details anti-ANGPTL4 Antibody

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Binding Specificity: AA 26-406

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANGPTL4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Angiopoietin-related protein 4 protein (26-406AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ANGPTL4

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Alternative Name: ANGPTL4 (ANGPTL4 Products)

Synonyms: ANGPTL2 antibody, ARP4 antibody, FIAF antibody, HFARP antibody, NL2 antibody, PGAR antibody, pp1158 antibody, Arp4 antibody, Bk89 antibody, Fiaf antibody, Hfarp antibody, Ng27 antibody, Pgar antibody, Pgarg antibody, Pp1158 antibody, ANGPTL4 antibody, fiaf antibody, im:7144703 antibody, si:rp71-39b20.7 antibody, angiopoietin like 4 antibody, angiopoietin-like 4 antibody, ANGPTL4 antibody, Angptl4 antibody, angptl4 antibody

Background:

Background: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

Aliases: Angiopoietin like 4 antibody, Angiopoietin related protein 4 antibody, Angiopoietin-like protein 4 antibody, Angiopoietin-related protein 4 antibody, ANGL4_HUMAN antibody, ANGPT L2 antibody, ANGPT L4 antibody, ANGPTL2 antibody, Angptl4 antibody, ARP4 antibody, Fasting induced adipose factor antibody, FIAF antibody, HARP antibody, Hepatic angiopoietin related protein antibody, Hepatic fibrinogen/angiopoietin related protein antibody, Hepatic fibrinogen/angiopoietin-related protein antibody, HFARP antibody, NL2 antibody, Peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin related protein antibody, PGAR antibody, pp1158 antibody, PPARG angiopoietin related protein antibody, PSEC0166 antibody, TGQTL antibody, UNQ171 antibody, Weakly similar to angiopoietin 1 [H.sapiens] antibody

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha