APC1 antibody (AA 1-185)

Catalog No. ABIN7144071

Product Details anti-APC1 Antibody

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Binding Specificity: AA 1-185

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APC1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Anaphase-promoting complex subunit 10 protein (1-185AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for APC1

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Alternative Name: ANAPC1 (ANAPC1 Products)

Synonyms: APC1 antibody, MCPR antibody, TSG24 antibody, DDBDRAFT_0186456 antibody, DDBDRAFT_0234263 antibody, DDB_0186456 antibody, DDB_0234263 antibody, 2610021O03Rik antibody, AI047775 antibody, AI853536 antibody, AW547281 antibody, Apc1 antibody, Mcpr antibody, tsg24 antibody, EMBRYO DEFECTIVE 2771 antibody, MOP10.10 antibody, MOP10_10 antibody, anaphase promoting complex subunit 1 antibody, E3 ubiquitin ligase antibody, ANAPC1 antibody, Anapc1 antibody, CC1G_09696 antibody, anapc1 antibody, EMB2771 antibody

Background:

Background: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of \\\'Lys-11\\\'-linked polyubiquitin chains and, to a lower extent, the formation of \\\'Lys-48\\\'- and \\\'Lys-63\\\'-linked polyubiquitin chains.

Aliases: ANAPC 10 antibody, anapc10 antibody, Anaphase promoting complex 10 antibody, Anaphase promoting complex subunit 10 antibody, Anaphase-promoting complex subunit 10 antibody, Apc 10 antibody, APC10 antibody, APC10_HUMAN antibody, Cyclosome subunit 10 antibody, DKFZP564L0562 antibody, Doc 1 antibody, Doc1 antibody, Doc1, S. cerevisiae, homolog of antibody, OTTHUMP00000220297 antibody, OTTHUMP00000220298 antibody, OTTHUMP00000220299 antibody, OTTHUMP00000220300 antibody, OTTHUMP00000220303 antibody

UniProt: Q9UM13