ADRA2A antibody (AA 218-374) (HRP)

Catalog No. ABIN7143810

Product Details anti-ADRA2A Antibody (HRP)

Target: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Binding Specificity: AA 218-374

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRA2A antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Alpha-2A adrenergic receptor protein (218-374AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ADRA2A

Target: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Alternative Name: ADRA2A (ADRA2A Products)

Synonyms: ADRA2A antibody, AW122659 antibody, Adra-2 antibody, Adra-2a antibody, alpha(2A)AR antibody, alpha2-C10 antibody, alpha2A antibody, alpha2A-AR antibody, ADRA2 antibody, ADRA2R antibody, ADRAR antibody, ALPHA2AAR antibody, ZNF32 antibody, CA2-47 antibody, RATRG20 antibody, RG20 antibody, PORA2AR antibody, adrenoceptor alpha 2A antibody, alpha-2A adrenergic receptor-like antibody, adrenergic receptor, alpha 2a antibody, adra2a antibody, ADRA2A antibody, LOC100414445 antibody, Adra2a antibody

Background:

Background: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.

Aliases: ADA2A_HUMAN antibody, ADRA2 antibody, ADRA2A antibody, ADRA2R antibody, ADRAR antibody, Adrenergic alpha 2A receptor antibody, Alpha 2 adrenergic receptor subtype C10 antibody, Alpha 2A adrenergic receptor antibody, Alpha 2AAR subtype C10 antibody, Alpha-2 adrenergic receptor subtype C10 antibody, alpha-2-adrenergic receptor, platelet type antibody, Alpha-2A adrenergic receptor antibody, Alpha-2A adrenoceptor antibody, Alpha-2A adrenoreceptor antibody, Alpha-2AAR antibody, ALPHA2AAR antibody, OTTHUMP00000058849 antibody, ZNF32 antibody

UniProt: P08913

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity