Iba1 antibody (AA 2-147)

Catalog No. ABIN7143728

Product Details anti-Iba1 Antibody

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Binding Specificity: AA 2-147

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Iba1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Allograft inflammatory factor 1 protein (2-147AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Iba1

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Alternative Name: AIF1 (IBA1 Products)

Synonyms: AIF-1 antibody, IBA1 antibody, IRT-1 antibody, IRT1 antibody, AI607846 antibody, D17H6S50E antibody, G1 antibody, Iba1 antibody, Bart1 antibody, iba1 antibody, mrf-1 antibody, fa04b11 antibody, wu:fa04b11 antibody, AIF antibody, AIF1 antibody, aif1 antibody, allograft inflammatory factor 1 antibody, AIF1 antibody, Aif1 antibody, aif1 antibody

Background:

Background: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Aliases: AIF 1 antibody, AIF-1 antibody, Aif1 antibody, AIF1 protein antibody, AIF1_HUMAN antibody, Allograft inflammatory factor 1 antibody, Allograft inflammatory factor 1 splice variant G antibody, allograft inflammatory factor-1 splice variant Hara-1 antibody, balloon angioplasty responsive transcription antibody, BART 1 antibody, G1 antibody, G1 putative splice variant of allograft inflamatory factor 1 antibody, IBA 1 antibody, IBA1 antibody, interferon gamma responsive transcript antibody, Interferon responsive transcript 1 antibody, interferon responsive transcript factor 1 antibody, Ionized calcium binding adapter molecule 1 antibody, Ionized calcium-binding adapter molecule 1 antibody, ionized calcium-binding adapter molecule antibody, IRT 1 antibody, IRT1 antibody, Microglia response factor antibody, MRF1 antibody, Protein g1 antibody

UniProt: P55008

Pathways: Smooth Muscle Cell Migration