Scinderin antibody (AA 556-703)

Catalog No. ABIN7143550

Product Details anti-Scinderin Antibody

Target: Scinderin (SCIN)

Binding Specificity: AA 556-703

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Scinderin antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Adseverin protein (556-703AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Scinderin

Target: Scinderin (SCIN)

Alternative Name: SCIN (SCIN Products)

Synonyms: MGC81993 antibody, si:ch211-134n17.3 antibody, AW545522 antibody, adseverin antibody, Scind antibody, scinderin L homeolog antibody, scinderin antibody, adseverin antibody, scin.L antibody, SCIN antibody, scin antibody, LOC100496020 antibody, Scin antibody

Background:

Background: Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity).

Aliases: Adseverin antibody, ADSV_HUMAN antibody, KIAA1905 antibody, Scin antibody, Scinderin antibody

UniProt: Q9Y6U3

Pathways: Regulation of Actin Filament Polymerization