NUDT5 antibody (AA 34-166) (HRP)
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- Target See all NUDT5 Antibodies
- NUDT5 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 5 (NUDT5))
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Binding Specificity
- AA 34-166
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NUDT5 antibody is conjugated to HRP
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human ADP-sugar pyrophosphatase protein (34-166AA)
- Isotype
- IgG
- Top Product
- Discover our top product NUDT5 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- NUDT5 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 5 (NUDT5))
- Alternative Name
- NUDT5 (NUDT5 Products)
- Synonyms
- YSA1 antibody, YSA1H antibody, YSAH1 antibody, hYSAH1 antibody, NUDT5 antibody, wu:fe48a12 antibody, zgc:86930 antibody, nudix hydrolase 5 antibody, nudix hydrolase 5 L homeolog antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 5 antibody, NUDT5 antibody, Nudt5 antibody, nudt5.L antibody, nudt5 antibody
- Background
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Background: Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate (PubMed:27257257). In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP (PubMed:10567213, PubMed:10722730, PubMed:19699693, PubMed:21389046, PubMed:17052728). Can also hydrolyze other nucleotide sugars with low activity (PubMed:19699693, PubMed:21389046). In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate. Nuclear ATP synthesis takes place when dephosphorylated at Thr-45 (PubMed:27257257). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (PubMed:27257257). Does not play a role in U8 snoRNA decapping activity (By similarity). Binds U8 snoRNA (By similarity).
Aliases: ADP sugar pyrophosphatase antibody, ADP-sugar pyrophosphatase antibody, hYSAH 1 antibody, hYSAH1 antibody, Nucleoside diphosphate linked moiety X motif 5 antibody, Nucleoside diphosphate linked moiety X type motif 5 antibody, Nucleoside diphosphate-linked moiety X motif 5 antibody, Nudix (nucleoside diphosphate linked moiety X) type motif 5 antibody, Nudix motif 5 antibody, Nudix type motif 5 antibody, NUDT 5 antibody, Nudt5 antibody, NUDT5_HUMAN antibody, YSA1 antibody, YSA1H antibody
- UniProt
- Q9UKK9
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