Adrenomedullin antibody (AA 45-92)

Catalog No. ABIN7143430

Product Details anti-Adrenomedullin Antibody

Target: Adrenomedullin (ADM)

Binding Specificity: AA 45-92

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adrenomedullin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human ADM protein (45-92AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Adrenomedullin

Target: Adrenomedullin (ADM)

Alternative Name: ADM (ADM Products)

Synonyms: ADM antibody, Ap antibody, H39316 antibody, RATAP antibody, AM antibody, adrenomedullin antibody, ADM antibody, adm antibody, Adm antibody

Target Type: Hormone

Background:

Background: AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.

Aliases: Adm antibody, ADM precursor antibody, ADML_HUMAN antibody, Adrenomedullin antibody, AM antibody, PAMP antibody, Preproadrenomedullin antibody, Proadrenomedullin N-20 terminal peptide antibody, Proadrenomedullin N20 terminal peptide antibody, ProAM N terminal 20 peptide antibody, ProAM N-terminal 20 peptide antibody, ProAM N20 antibody, ProAM-N20 antibody, ProAMN20 antibody

UniProt: P35318

Pathways: Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation