ADCY6 antibody (AA 9-118) (HRP)

Catalog No. ABIN7143337

Product Details anti-ADCY6 Antibody (HRP)

Target: ADCY6 (Adenylate Cyclase 6 (ADCY6))

Binding Specificity: AA 9-118

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY6 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Adenylate cyclase type 6 protein (9-118AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ADCY6

Target: ADCY6 (Adenylate Cyclase 6 (ADCY6))

Alternative Name: ADCY6 (ADCY6 Products)

Synonyms: ADCY6 antibody, adcy6 antibody, AC6 antibody, mKIAA0422 antibody, ACVI antibody, ADCYB antibody, adenylate cyclase 6 L homeolog antibody, adenylate cyclase 6 antibody, adenylate cyclase 6a antibody, adcy6.L antibody, ADCY6 antibody, adcy6a antibody, adcy6 antibody, Adcy6 antibody

Background:

Background: Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed:17916776, PubMed:17110384). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells (PubMed:17916776). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion (By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA. This promotes increased phosphorylation of various proteins, including AKT. Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility. May contribute to normal heart function (By similarity). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol (PubMed:17916776). Contributes to bone cell responses to mechanical stimuli (By similarity).

Aliases: AC6 antibody, ACVI antibody, ADCY 6 antibody, Adcy6 antibody, ADCY6_HUMAN antibody, ADCYB antibody, Adenylate cyclase 6 antibody, Adenylate cyclase type 6 antibody, Adenylate cyclase type VI antibody, Adenylyl cyclase 6 antibody, ATP pyrophosphate lyase 6 antibody, ATP pyrophosphate-lyase 6 antibody, Ca(2+) inhibitable adenylyl cyclase antibody, Ca(2+)-inhibitable adenylyl cyclase antibody, DKFZp779F075 antibody, EC 4.6.1.1 antibody, KIAA0422 antibody

UniProt: O43306

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma