ADCY1 antibody (AA 897-1136)

Catalog No. ABIN7143324

Product Details anti-ADCY1 Antibody

Target: ADCY1 (Adenylate Cyclase 1 (Brain) (ADCY1))

Binding Specificity: AA 897-1136

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Adenylate cyclase type 10 protein (897-1136AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ADCY1

Target: ADCY1 (Adenylate Cyclase 1 (Brain) (ADCY1))

Alternative Name: ADCY1 (ADCY1 Products)

Synonyms: AC1 antibody, D11Bwg1392e antibody, I-AC antibody, brl antibody, mKIAA4070 antibody, Ac1 antibody, adenylate cyclase 1 antibody, adenylate cyclase type 1 antibody, adenylate cyclase 1 (brain) antibody, ADCY1 antibody, LOC100449504 antibody, adcy1 antibody, Adcy1 antibody

Background:

Background: Catalyzes the formation of the signaling molecule cAMP (PubMed:12609998, PubMed:15659711, PubMed:24616449, PubMed:25040695, PubMed:24567411). May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels (PubMed:15659711, PubMed:17591988). Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization (By similarity). Involved in ciliary beat regulation (PubMed:17591988).

Aliases: ADCY10 antibody, SAC antibody, Adenylate cyclase type 10 antibody, EC 4.6.1.1 antibody, AH-related protein antibody, Adenylate cyclase homolog antibody, Germ cell soluble adenylyl cyclase antibody, hsAC antibody, sAC antibody, Testicular soluble adenylyl cyclase antibody

UniProt: Q96PN6

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma