ARPC3 antibody (AA 2-175) (HRP)
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- Target See all ARPC3 Antibodies
- ARPC3 (Actin Related Protein 2/3 Complex, Subunit 3, 21kDa (ARPC3))
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Binding Specificity
- AA 2-175
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARPC3 antibody is conjugated to HRP
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Actin-related protein 2/3 complex subunit 3 protein (2-175AA)
- Isotype
- IgG
- Top Product
- Discover our top product ARPC3 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ARPC3 (Actin Related Protein 2/3 Complex, Subunit 3, 21kDa (ARPC3))
- Alternative Name
- ARPC3 (ARPC3 Products)
- Synonyms
- ARC21 antibody, p21-Arc antibody, 1110006A04Rik antibody, 21kDa antibody, AA408672 antibody, AI788639 antibody, p21-Ar antibody, p21Arc antibody, arc21 antibody, p21-arc antibody, zgc:86828 antibody, actin related protein 2/3 complex subunit 3 antibody, actin related protein 2/3 complex, subunit 3 antibody, actin related protein 2/3 complex subunit 3 L homeolog antibody, actin related protein 2/3 complex, subunit 3, 21kDa antibody, actin related protein 2/3 complex subunit 3 pseudogene antibody, actin-related protein 2/3 complex subunit 3 antibody, actin-related protein 2/3 complex subunit 3 pseudogene antibody, ARPC3 antibody, Arpc3 antibody, arpc3.L antibody, LOC738738 antibody, arpc3 antibody, LOC100036831 antibody, LOC100341254 antibody
- Background
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Background: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).
Aliases: ARPC3 antibody, ARC21Actin-related protein 2/3 complex subunit 3 antibody, Arp2/3 complex 21 kDa subunit antibody, p21-ARC antibody
- UniProt
- O15145
- Pathways
- RTK Signaling, Regulation of Actin Filament Polymerization
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