CYP8B1 antibody (AA 303-440)
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- Target See all CYP8B1 Antibodies
- CYP8B1 (Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1))
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Binding Specificity
- AA 303-440
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYP8B1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Rat
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase protein (303-440AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CYP8B1 (Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1))
- Alternative Name
- CYP8B1 (CYP8B1 Products)
- Synonyms
- MGC64456 antibody, CYP8B antibody, CP8B antibody, CYP12 antibody, cytochrome P450 family 8 subfamily B member 1 antibody, cytochrome P450 family 8 subfamily B member 1 S homeolog antibody, cytochrome P450, family 8, subfamily B, polypeptide 1 antibody, cytochrome P450, family 8, subfamily b, polypeptide 1 antibody, Cyp8b1 antibody, cyp8b1.S antibody, CYP8B1 antibody
- Background
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Background: Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.
Aliases: 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase antibody, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase antibody, CP8B antibody, CP8B1_HUMAN antibody, CYP12 antibody, CYP8B1 antibody, CYPVIIIB1 antibody, Cytochrome P450 8B1 antibody, Cytochrome P450 subfamily VIIIB (sterol 12 alpha hydroxylase) polypeptide 1 antibody, Cytochrome P450, family 8, subfamily B, polypeptide 1 antibody, Sterol 12-alpha-hydroxylase antibody
- UniProt
- Q9UNU6
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