RPL13A antibody (AA 63-190) (Biotin)

Catalog No. ABIN7142745

Product Details anti-RPL13A Antibody (Biotin)

Target: RPL13A (Ribosomal Protein L13a (RPL13A))

Binding Specificity: AA 63-190

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPL13A antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human 60S ribosomal protein L13a protein (63-190AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RPL13A

Target: RPL13A (Ribosomal Protein L13a (RPL13A))

Alternative Name: RPL13A (RPL13A Products)

Synonyms: 1810026N22Rik antibody, Tstap198-7 antibody, tum-antigen antibody, L13A antibody, TSTA1 antibody, CG1475 antibody, Dmel\\CG1475 antibody, L13a2 antibody, M(3)83B antibody, Rp L13A antibody, anon-EST:Posey125 antibody, anon-EST:fe1A5 antibody, bs25f04.y1 antibody, cg1475 antibody, MGC54018 antibody, GB16111 antibody, hm:zehp0384 antibody, wu:fa95e06 antibody, wu:fb08g07 antibody, wu:fd05d08 antibody, DDBDRAFT_0217704 antibody, DDBDRAFT_0231192 antibody, DDB_0217704 antibody, DDB_0231192 antibody, ribosomal protein L13A antibody, ribosomal protein L13a antibody, Ribosomal protein L13A antibody, ribosomal protein L13a S homeolog antibody, 60S ribosomal protein L13a antibody, ribosomal protein 13a antibody, ribosomal 60S subunit protein L13A antibody, Ribosomal protein L13a, component of cytosolic 80S ribosome and 60S large subunit antibody, S60 ribosomal protein L13a antibody, Rpl13a antibody, RPL13A antibody, RpL13A antibody, rpl13a.S antibody, rpl13a antibody, LOC551418 antibody, LOC663151 antibody, RPL13a antibody

Background:

Background: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3\'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.

Aliases: RPL13A antibody, 60S ribosomal protein L13a antibody, 23 kDa highly basic protein antibody, Large ribosomal subunit protein uL13 antibody

UniProt: P40429