PSMC5 antibody (Regulatory Subunit 8)
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- Target See all PSMC5 Antibodies
- PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))
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Binding Specificity
- AA 253-324, Regulatory Subunit 8
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMC5 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human 26S proteasome regulatory subunit 8 protein (253-324AA)
- Isotype
- IgG
- Top Product
- Discover our top product PSMC5 Primary Antibody
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- Application Notes
- Recommended dilution: WB:1:2000-1:10000, IF:1:50-1:500,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))
- Alternative Name
- PSMC5 (PSMC5 Products)
- Synonyms
- mSUG1 antibody, S8 antibody, SUG-1 antibody, SUG1 antibody, TBP10 antibody, TRIP1 antibody, p45 antibody, p45/SUG antibody, wu:fa14g03 antibody, wu:fb23a11 antibody, zgc:92464 antibody, sug-1 antibody, sug1 antibody, tbp10 antibody, Sug1 antibody, PSMC5 antibody, xsug1 antibody, protease (prosome, macropain) 26S subunit, ATPase 5 antibody, proteasome 26S subunit, ATPase 5 antibody, proteasome 26S subunit, ATPase 5 L homeolog antibody, proteasome 26S subunit, ATPase 5 S homeolog antibody, Psmc5 antibody, PSMC5 antibody, psmc5 antibody, psmc5.L antibody, psmc5.S antibody
- Background
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Background: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
Aliases: 26S protease regulatory subunit 8 antibody, 26S proteasome AAA-ATPase subunit RPT6 antibody, Cim3 antibody, MSUG1 protein antibody, p45 antibody, p45/SUG antibody, Proteasome 26S ATPase subunit 5 antibody, Proteasome 26S subunit ATPase 5 antibody, Proteasome prosome macropain 26S subunit ATPase 5 antibody, Proteasome subunit p45 antibody, PRS8_HUMAN antibody, PSMC5 antibody, Rpt6 antibody, S8 antibody, SUG1 antibody, Tat binding protein homolog 10 antibody, TBP10 antibody, Thyroid hormone receptor interacting protein 1 antibody, Thyroid hormone receptor-interacting protein 1 antibody, Thyroid receptor interactor 1 antibody, TRIP1 antibody, TRIP1(SUG1) antibody
- UniProt
- P62195
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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