RuvA antibody (AA 1-203) (Biotin)

Catalog No. ABIN7141552

Product Details anti-RuvA Antibody (Biotin)

Target: RuvA

Binding Specificity: AA 1-203

Reactivity: E. coli

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RuvA antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: E. coli

Purification: >95%, Protein G purified

Immunogen: Recombinant Escherichia coli Holliday junction ATP-dependent DNA helicase RuvA protein (1-203AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RuvA

Target: RuvA

Abstract: RuvA Products

Background:

Background: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA.

Aliases: ruvA antibody, b1861 antibody, JW1850 antibody, Holliday junction ATP-dependent DNA helicase RuvA antibody, EC 3.6.4.12 antibody

UniProt: P0A809