RuvA antibody (AA 1-203)
-
- Target See all RuvA products
- RuvA
- Binding Specificity
- AA 1-203
- Reactivity
- E. coli
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This RuvA antibody is un-conjugated
- Application
- ELISA
- Cross-Reactivity
- E. coli
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Escherichia coli Holliday junction ATP-dependent DNA helicase RuvA protein (1-203AA)
- Isotype
- IgG
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- RuvA
- Abstract
- RuvA Products
- Background
-
Background: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA.
Aliases: ruvA antibody, b1861 antibody, JW1850 antibody, Holliday junction ATP-dependent DNA helicase RuvA antibody, EC 3.6.4.12 antibody
- UniProt
- P0A809
-