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RuvA antibody (AA 1-203)

Reactivity: E. coli ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7141551
  • Target See all RuvA products
    RuvA
    Binding Specificity
    AA 1-203
    Reactivity
    E. coli
    Host
    • 4
    Rabbit
    Clonality
    • 4
    Polyclonal
    Conjugate
    • 2
    • 1
    • 1
    This RuvA antibody is un-conjugated
    Application
    ELISA
    Cross-Reactivity
    E. coli
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Escherichia coli Holliday junction ATP-dependent DNA helicase RuvA protein (1-203AA)
    Isotype
    IgG
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    RuvA
    Abstract
    RuvA Products
    Background

    Background: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA.

    Aliases: ruvA antibody, b1861 antibody, JW1850 antibody, Holliday junction ATP-dependent DNA helicase RuvA antibody, EC 3.6.4.12 antibody

    UniProt
    P0A809
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