Dystonin antibody

Catalog No. ABIN7141251

Product Details anti-Dystonin Antibody

Target: Dystonin (DST)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Dystonin antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Human

Purification: Protein G purified

Immunogen: Recombinant DST Protein

Clone: 2F7B3

Isotype: IgG1, IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Dystonin

Target: Dystonin (DST)

Alternative Name: DST (DST Products)

Background:

Background: This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been known that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.

Aliases: Dystonin,Bullous pemphigoid antigen,BPA

UniProt: Q03001