LOC105923162 antibody (AA 1-136)

Catalog No. ABIN7140904

Product Details anti-LOC105923162 Antibody

Target: LOC105923162 (Lactose-Binding Lectin l-2-Like (LOC105923162))

Binding Specificity: AA 1-136

Reactivity: Malayan pit viper (Calloselasma rhodostoma)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOC105923162 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Cross-Reactivity: Malayan pit viper (Calloselasma rhodostoma)

Purification: >95%, Protein G purified

Immunogen: Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit alpha protein (1-136AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LOC105923162

Target: LOC105923162 (Lactose-Binding Lectin l-2-Like (LOC105923162))

Alternative Name: Snaclec rhodocytin subunit alpha (LOC105923162 Products)

Background:

Background: Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial.

Aliases: antibody, Snaclec rhodocytin subunit alpha antibody, Aggretin alpha chain antibody, Rhodoaggretin subunit alpha antibody

UniProt: Q9I841