MEST antibody

Catalog No. ABIN7140340

Product Details anti-MEST Antibody

Target: MEST (Mesoderm Specific Transcript (MEST))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MEST antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Cross-Reactivity: Human, Mouse, Pig, Rabbit

Purification: Affinity purified

Immunogen: Purified recombinant human PEG10 protein fragments expressed in E.coli.

Isotype: IgG1, IgG1 kappa

Application Details

Application Notes: Recommended dilution:WB:1:500-1:5000,IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine ( pH 7.4, 150 mM NaCl) with 0.2 % sodium azide, 50 %,glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MEST

Target: MEST (Mesoderm Specific Transcript (MEST))

Alternative Name: PEG1 (MEST Products)

Synonyms: AA408879 antibody, AI256745 antibody, Peg1 antibody, PEG1 antibody, mesoderm specific transcript antibody, Mest antibody, MEST antibody

Background:

Background: This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation.

Aliases: EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3

UniProt: Q86TG7