VPS36 antibody (AA 87-105)

Catalog No. ABIN7140211

Product Details anti-VPS36 Antibody

Target: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Binding Specificity: AA 87-105

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS36 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Peptide sequence from Human Vacuolar protein-sorting-associated protein 36 protein (87-105AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for VPS36

Target: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Alternative Name: VPS36 (VPS36 Products)

Background:

Background: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.

Aliases: C13orf9 antibody, CGI 145 antibody, EAP45 antibody, ELL associated protein of 45 kDa antibody, ELL-associated protein of 45 kDa antibody, ESCRT-II complex subunit VPS36 antibody, Vacuolar protein sorting associated protein 36 antibody, Vacuolar protein-sorting-associated protein 36 antibody, Vps36 antibody, VPS36_HUMAN antibody

UniProt: Q86VN1