Importin 9 antibody (AA 158-176) (Biotin)

Catalog No. ABIN7140095

Product Details anti-Importin 9 Antibody (Biotin)

Target: Importin 9 (IPO9)

Binding Specificity: AA 158-176

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Importin 9 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Peptide sequence from Human Ran-binding protein 9 protein (158-176AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Importin 9

Target: Importin 9 (IPO9)

Alternative Name: RANBP9 (IPO9 Products)

Synonyms: Imp9 antibody, 0710008K06Rik antibody, AI845704 antibody, C78347 antibody, Ranbp9 antibody, mKIAA1192 antibody, zgc:66429 antibody, wu:fc23d12 antibody, MGC81741 antibody, IPO9 antibody, DDBDRAFT_0205722 antibody, DDBDRAFT_0229883 antibody, DDB_0205722 antibody, DDB_0229883 antibody, RGD1561940 antibody, RanBPM antibody, RanBP9 antibody, bpm-l antibody, bpm90 antibody, ranbp9 antibody, ranbp9-a antibody, ranbp9-b antibody, ranbp9b antibody, cb457 antibody, zgc:158650 antibody, importin 9 antibody, importin 9 L homeolog antibody, RAN binding protein 9 antibody, RAN binding protein 9 L homeolog antibody, IPO9 antibody, Ipo9 antibody, ipo9 antibody, ipo9.L antibody, cnrP antibody, Ranbp9 antibody, ranbp9.L antibody, RANBP9 antibody, ranbp9 antibody

Background:

Background: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA (By similarity).

Aliases: B cell antigen receptor Ig beta associated protein 1 antibody, BPM 90 antibody, BPM L antibody, BPM-L antibody, BPM90 antibody, BPML antibody, IBAP 1 antibody, Imp 9 antibody, Importin 9 antibody, Novel centrosomal protein RanBPM antibody, RAN binding protein 9 antibody, Ran binding protein centrosomal antibody, Ran Binding Protein in the Microtubule organizing center antibody, Ran binding protein M antibody, Ran BP9 antibody, Ran-binding protein 9 antibody, Ran-binding protein M antibody, RANB9_HUMAN antibody, RanBP 7 antibody, RANBP 9 antibody, RanBP7 antibody, RanBP9 antibody, RanBPM antibody

UniProt: Q96S59

Pathways: Protein targeting to Nucleus