MDFIC antibody (AA 35-53) (Biotin)

Catalog No. ABIN7139929

Product Details anti-MDFIC Antibody (Biotin)

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Binding Specificity: AA 35-53

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MDFIC antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Peptide sequence from Human MyoD family inhibitor domain-containing protein (35-53AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MDFIC

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Alternative Name: MDFIC (MDFIC Products)

Synonyms: HIC antibody, Kdt1 antibody, Mdfid antibody, MyoD family inhibitor domain containing antibody, MyoD family inhibitor domain containing S homeolog antibody, MDFIC antibody, Mdfic antibody, mdfic.S antibody

Background:

Background: Acts as a transcriptional activator or repressor. Inhibits the transcriptional activation of Zic family proteins ZIC1, ZIC2 and ZIC3. Retains nuclear Zic proteins ZIC1, ZIC2 and ZIC3 in the cytoplasm. Modulates the expression from both cellular and viral promoters. Down-regulates Tat-dependent transcription of the human immunodeficiency virus type 1 (HIV-1) LTR by interacting with HIV-1 Tat and Rev and impairing their nuclear import, probably by rendering the NLS domains inaccessible to importin-beta. Also stimulates activation of human T-cell leukemia virus type I (HTLV-I) LTR. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways.

Aliases: MDFIC antibody, MyoD family inhibitor domain-containing protein antibody, I-mfa domain-containing protein antibody, hIC antibody

UniProt: Q9P1T7