AMOTL2 antibody (AA 718-737) (Biotin)

Catalog No. ABIN7139726

Product Details anti-AMOTL2 Antibody (Biotin)

Target: AMOTL2 (Angiomotin Like 2 (AMOTL2))

Binding Specificity: AA 718-737

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMOTL2 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Peptide sequence from Human Angiomotin-like protein 2 protein (718-737AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AMOTL2

Target: AMOTL2 (Angiomotin Like 2 (AMOTL2))

Alternative Name: AMOTL2 (AMOTL2 Products)

Synonyms: LCCP antibody, AW549739 antibody, C79691 antibody, Lccp antibody, MASCOT antibody, mKIAA0989 antibody, zgc:154007 antibody, angiomotin like 2 antibody, angiomotin-like 2 antibody, angiomotin like 2b antibody, AMOTL2 antibody, Amotl2 antibody, amotl2 antibody, amotl2b antibody

Background:

Background: Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.

Aliases: AMOL2_HUMAN antibody, Amotl2 antibody, angiomotin like 2 antibody, Angiomotin-like protein 2 antibody, KIAA0989 antibody, LCCP antibody, Leman coiled coil protein antibody, Leman coiled-coil protein antibody

UniProt: Q9Y2J4