HIST1H2BB antibody (acLys5)

Catalog No. ABIN7139184

Product Details anti-HIST1H2BB Antibody

Target: HIST1H2BB (Histone Cluster 1, H2bb (HIST1H2BB))

Binding Specificity: acLys5

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H2BB antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Peptide sequence around site of Acetyl-Lys (5) derived from Human Histone H2B type 1-B

Isotype: IgG

Application Details

Application Notes: Recommended dilution: ICC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HIST1H2BB

Target: HIST1H2BB (Histone Cluster 1, H2bb (HIST1H2BB))

Alternative Name: HIST1H2BB (HIST1H2BB Products)

Synonyms: H2B.1 antibody, H2B/f antibody, H2BFF antibody, H2b-143 antibody, histone cluster 1 H2B family member b antibody, histone cluster 1, H2bb antibody, HIST1H2BB antibody, Hist1h2bb antibody

Background:

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Aliases: HIST1H2BB antibody, H2BFFHistone H2B type 1-B antibody, Histone H2B.1 antibody, Histone H2B.f antibody, H2B/f antibody

UniProt: P33778

Pathways: Telomere Maintenance