EPH Receptor A3 antibody (pTyr779, pTyr833)

Catalog No. ABIN7139068

Product Details anti-EPH Receptor A3 Antibody

Target: EPH Receptor A3 (EPHA3)

Binding Specificity: pTyr779, pTyr833

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 779/833 (E-A-Y(p)-T-T)/(Q-D-V(p)-I-K) derived from Human EPHA3/4/5.

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EPH Receptor A3

Target: EPH Receptor A3 (EPHA3)

Alternative Name: EPHA3 (EPHA3 Products)

Synonyms: EK4 antibody, ETK antibody, ETK1 antibody, HEK antibody, HEK4 antibody, TYRO4 antibody, EPHA3 antibody, AW492086 antibody, Cek4 antibody, End3 antibody, Hek antibody, Hek4 antibody, Mek4 antibody, Tyro4 antibody, CEK4 antibody, EPH receptor A3 antibody, ephrin type-A receptor 3 antibody, Eph receptor A3 antibody, EPHA3 antibody, LOC100439679 antibody, Epha3 antibody

Background:

Background:

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands.

Wicks I.P., Proc. Natl. Acad. Sci. U.S.A. 89:1611-1615(1992).
Chiari R., Cancer Res. 60:4855-4863(2000).
Boyd A.W., J. Biol. Chem. 267:3262-3267(1992).

Aliases: AW492086 antibody, Cek4 antibody, EC 2.7.10.1 antibody, EK4 antibody, End3 antibody, Eph receptor A3 antibody, EPH-like kinase 4 antibody, EPH-like tyrosine kinase 1 antibody, EPHA3 antibody, EPHA3_HUMAN antibody, Ephrin receptor EphA3 antibody, Ephrin type-A receptor 3 antibody, ETK 1 antibody, ETK antibody, ETK1 antibody, HEK 4 antibody, HEK antibody, HEK4 antibody, Human embryo kinase 1 antibody, Human embryo kinase antibody, Mek4 antibody, MGC109882 antibody, Receptor tyrosine kinase HEK antibody, Testicular tissue protein Li 64 antibody, Tyro 4 antibody, Tyro4 antibody, TYRO4 protein tyrosine kinase antibody, Tyrosine protein kinase receptor ETK 1 antibody, Tyrosine-protein kinase receptor ETK1 antibody, Tyrosine-protein kinase TYRO4 antibody

UniProt: P29320

Pathways: RTK Signaling, Regulation of Cell Size