Phospholipase C gamma 1 antibody (pTyr771)

Catalog No. ABIN7139066

Product Details anti-Phospholipase C gamma 1 Antibody

Target: Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

Binding Specificity: pTyr771

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C gamma 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 771 (P-D-Y(p)-G-A) derived from Human PLC-g1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000, IF:1:100-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Phospholipase C gamma 1

Target: Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

Alternative Name: PLCG1 (PLCG1 Products)

Synonyms: NCKAP3 antibody, PLC-II antibody, PLC1 antibody, PLC148 antibody, PLCgamma1 antibody, plc1 antibody, nckap3 antibody, plc-ii antibody, plc148 antibody, plcgamma1 antibody, PPLCA antibody, AI894140 antibody, Cded antibody, Plc-1 antibody, Plc-gamma1 antibody, Plcg-1 antibody, fj46f04 antibody, wu:fj46f04 antibody, wu:fj57a05 antibody, phospholipase C gamma 1 antibody, phospholipase C gamma 1 L homeolog antibody, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 antibody, phospholipase C, gamma 1 antibody, PLCG1 antibody, plcg1.L antibody, LOC100633163 antibody, Plcg1 antibody, plcg1 antibody

Background:

Background: PLC-gamma is a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

Yue, C. et al. (1998) J. Biol. Chem. 273, 18023-18027.
Margolis, B. et al. (1989) Cell 57, 1101-1107.
Yue, C. et al. (2000) J. Biol. Chem. 275, 30220-30225.

Aliases: 1 phosphatidyl D myo inositol 4 5 bisphosphate antibody, 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1 antibody, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 antibody, Inositoltrisphosphohydrolase antibody, Monophosphatidylinositol phosphodiesterase antibody, NCKAP3 antibody, Phosphatidylinositol phospholipase C antibody, Phosphoinositidase C antibody, Phosphoinositide phospholipase C antibody, Phosphoinositide phospholipase C-gamma-1 antibody, Phospholipase C 148 antibody, Phospholipase C gamma 1 antibody, Phospholipase C-gamma-1 antibody, Phospholipase C-II antibody, PLC gamma 1 antibody, PLC II antibody, PLC-148 antibody, PLC-gamma-1 antibody, PLC-II antibody, PLC1 antibody, PLC148 antibody, Plcg1 antibody, PLCG1_HUMAN antibody, PLCgamma1 antibody

UniProt: P19174

Pathways: RTK Signaling, WNT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling