Caveolin 2 antibody (pTyr27)

Catalog No. ABIN7138965

Product Details anti-Caveolin 2 Antibody

Target: Caveolin 2 (CAV2)

Binding Specificity: pTyr27

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 27 (L-E-Y(p)-A-D) derived from Human Caveolin 2.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Caveolin 2

Target: Caveolin 2 (CAV2)

Alternative Name: CAV2 (CAV2 Products)

Synonyms: CAV antibody, AI447843 antibody, cav-2 antibody, zgc:86696 antibody, wu:fc52e01 antibody, caveolin-2 antibody, CAV-2 antibody, Caveolin-2 antibody, Cav-2 antibody, cav antibody, cav2 antibody, caveolin 2 antibody, caveolin 2 L homeolog antibody, caveolin-2 antibody, Caveolin-2 antibody, CAV2 antibody, Cav2 antibody, cav2.L antibody, cav2 antibody, LOC100093133 antibody, cav-2 antibody

Background:

Background:

The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.

Scherer P.E., Proc. Natl. Acad. Sci. U.S.A. 93:131-135(1996).
Scherer P.E., J. Biol. Chem. 272:29337-29346(1997).
Engelman J.A., FEBS Lett. 448:221-230(1999).

Aliases: CAV antibody, CAV2 antibody, CAV2_HUMAN antibody, Caveolae protein 20 kD antibody, Caveolin 2 antibody, Caveolin 2 isoform a and b antibody, Caveolin-2 antibody, MGC12294 antibody, OTTHUMP00000025032 antibody, OTTHUMP00000195982 antibody

UniProt: P51636

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development