WASF1 antibody (pTyr125)

Catalog No. ABIN7138927

Product Details anti-WASF1 Antibody

Target: WASF1 (WAS Protein Family, Member 1 (WASF1))

Binding Specificity: pTyr125

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WASF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 125 (E-T-Y(p)-D-V) derived from Human WAVE1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for WASF1

Target: WASF1 (WAS Protein Family, Member 1 (WASF1))

Alternative Name: WASF1 (WASF1 Products)

Background:

Background: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.

Aliases: WASP family, verprolin homology domain-containing protein 1 antibody, WASP family member 1 antibody, FLJ31482 antibody, homology of dictyostelium scar 1 antibody, KIAA0269 antibody, Protein WAVE-1 antibody, Protein WAVE1 antibody, scar, Dictyostelium, homology of, 1 antibody, SCAR1 antibody, Similar to a plant extensin like protein antibody, Verprolin homology domain containing protein 1 antibody, Verprolin homology domain-containing protein 1 antibody, WAS protein family, member 1 antibody, Wasf1 antibody, WASF1_HUMAN antibody, WASL antibody, WASP family 1 antibody, WASP family protein member 1 antibody, WASP family, verprolin homology domain-containing protein antibody, WAVE antibody, WAVE1 antibody, Wiskott Aldrich syndrome protein family member 1 antibody, Wiskott-Aldrich syndrome protein family member 1 antibody

UniProt: Q92558

Pathways: RTK Signaling, Regulation of Actin Filament Polymerization