BIK antibody (pThr33)

Catalog No. ABIN7138834

Product Details anti-BIK Antibody

Target: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Binding Specificity: pThr33

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine 33 (G-M-T(p)-D-S) derived from Human BIK.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BIK

Target: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Alternative Name: BIK (BIK Products)

Synonyms: BIK antibody, Biklk antibody, Blk antibody, Nbk antibody, BIP1 antibody, BP4 antibody, NBK antibody, si:dkey-31f5.6 antibody, BCL2 interacting killer antibody, BCL2-interacting killer antibody, BCL2-interacting killer (apoptosis-inducing) antibody, BIK antibody, Bik antibody, bik antibody

Background:

Background: Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.

Aliases: Apoptosis inducer NBK antibody, BBC1 antibody, Bcl-2-interacting killer antibody, BCL2 interacting killer antibody, bhikhari antibody, BIK antibody, Bik-like killer protein antibody, BIK_HUMAN antibody, BIP 1 antibody, BiP1 antibody, BP 4 antibody, BP4 antibody, cb 60 antibody, NBK antibody

UniProt: Q13323

Pathways: Positive Regulation of Endopeptidase Activity