C-JUN antibody (pThr239)

Catalog No. ABIN7138815

Product Details anti-C-JUN Antibody

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Binding Specificity: pThr239

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C-JUN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine 239 (G-E-T(p)-P-P) derived from Human c-Jun.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for C-JUN

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Alternative Name: JUN (JUN Products)

Background:

Background: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.

Boyle W J, et al. (1991) Cell. 64(3): 573-584.
Binetruy B, et al. (1991) Nature. 351: 122-127.
Smeal T, et al. (1991) Nature. 354:494-496.
Derijard B, et al. (1994) Cell. 76:1025-1037.
Kyriakis J M, et al. (1994) Nature. 369: 156-160.

Aliases: Activator protein 1 antibody, AP 1 antibody, AP-1 antibody, AP1 antibody, cJun antibody, Enhancer Binding Protein AP1 antibody, Jun Activation Domain Binding Protein antibody, JUN antibody, Jun oncogene antibody, JUN protein antibody, Jun proto oncogene antibody, JUN_HUMAN antibody, JUNC antibody, Oncogene JUN antibody, p39 antibody, Proto oncogene c jun antibody, Proto oncogene cJun antibody, Proto-oncogene c-jun antibody, Transcription Factor AP 1 antibody, Transcription factor AP-1 antibody, Transcription Factor AP1 antibody, V jun avian sarcoma virus 17 oncogene homolog antibody, V jun sarcoma virus 17 oncogene homolog (avian) antibody, V jun sarcoma virus 17 oncogene homolog antibody, V-jun avian sarcoma virus 17 oncogene homolog antibody, vJun Avian Sarcoma Virus 17 Oncogene Homolog antibody

UniProt: P05412

Pathways: MAPK Signaling, RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins