CEBPA antibody (pThr230)

Catalog No. ABIN7138811

Product Details anti-CEBPA Antibody

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Binding Specificity: pThr230

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEBPA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine 230 (P-P-T(p)-P-V) derived from Human C/EBP-alpha.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CEBPA

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Alternative Name: CEBPA (CEBPA Products)

Synonyms: C/EBP-alpha antibody, CEBP antibody, C/ebpalpha antibody, CBF-A antibody, Cebp antibody, DBPCEP antibody, c/ebpa antibody, cb1062 antibody, wu:fj20f03 antibody, C/EBP antibody, C/EBPalpha antibody, xC/EBP antibody, cC/EBP antibody, C/EBP alpha antibody, CCAAT/enhancer binding protein alpha antibody, CCAAT/enhancer binding protein (C/EBP), alpha antibody, CCAAT/enhancer binding protein alpha L homeolog antibody, CEBPA antibody, Cebpa antibody, cebpa antibody, cebpa.L antibody

Background:

Background: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.Xanthopoulos K.G. Biochem. Biophys. Res. Commun. 215:106-113(1995)Schalwijk J. Biol. Chem. Hoppe-Seyler 378:373-379(1997)SeattleSNPs variation discovery resource Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases

Aliases: Apoptotic cysteine protease antibody, Apoptotic protease Mch 5 antibody, C/EBP alpha antibody, C/ebpalpha antibody, CAP4 antibody, Caspase 8 precursor antibody, CBF-A antibody, CCAAT Enhancer Binding Protein alpha antibody, CCAAT/enhancer binding protein (C/EBP), alpha antibody, CCAAT/enhancer-binding protein alpha antibody, CEBP antibody, CEBP A antibody, CEBP alpha antibody, Cebpa antibody, CEBPA_HUMAN antibody, FADD homologous ICE/CED 3 like protease antibody, FADD like ICE antibody, FLICE antibody, ICE like apoptotic protease 5 antibody, ICE8 antibody, MACH antibody, MCH5 antibody, MORT1 associated CED 3 homolog antibody

UniProt: P49715

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation