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EIF4B antibody (pSer422)

EIF4B Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7138611
  • Target See all EIF4B Antibodies
    EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))
    Binding Specificity
    • 18
    • 14
    • 8
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer422
    Reactivity
    • 94
    • 47
    • 32
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    Human
    Host
    • 80
    • 12
    • 2
    Rabbit
    Clonality
    • 80
    • 14
    Polyclonal
    Conjugate
    • 53
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EIF4B antibody is un-conjugated
    Application
    • 79
    • 39
    • 32
    • 17
    • 17
    • 17
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human, Mouse
    Purification
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    Immunogen
    Peptide sequence around phosphorylation site of Serine 422 (T-G-S(p)-E-S) derived from Human eIF4B.
    Isotype
    IgG
    Top Product
    Discover our top product EIF4B Primary Antibody
  • Application Notes
    WB:1:500-1:1000, IHC:1:50-1:100,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))
    Alternative Name
    EIF4B (EIF4B Products)
    Background

    Background: Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

    Gingras, A.C. et al. (2001) Genes Dev. 15, 807-826.
    Duncan, R. and Hershey, J.W. (1985) J. Biol. Chem. 260, 5493-5497.
    Duncan, R.F. and Hershey, J.W. (1989) J. Cell Biol. 109, 1467-1481.

    Aliases: 2310046H11Rik antibody, AL024095 antibody, C85189 antibody, EIF 4B antibody, eIF-4B antibody, EIF4B antibody, Eukaryotic initiation factor 4B antibody, Eukaryotic translation initiation factor 4B antibody, IF4B_HUMAN antibody, PRO1843 antibody

    UniProt
    P23588
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