HDAC2 antibody (pSer394)

Catalog No. ABIN7138595

Product Details anti-HDAC2 Antibody

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Binding Specificity: pSer394

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 394 (E-D-S(p)-G-D) derived from Human HDAC2.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HDAC2

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Alternative Name: HDAC2 (HDAC2 Products)

Synonyms: HD2 antibody, RPD3 antibody, YAF1 antibody, D10Wsu179e antibody, Yy1bp antibody, mRPD3 antibody, HISTONE DEACETYLASE antibody, T1N24.9 antibody, T1N24_9 antibody, histone deacetylase 2 antibody, histone deacetylase 2 antibody, histone deacetylase 2 S homeolog antibody, HDAC2 antibody, Hdac2 antibody, hdac2.S antibody, HDA2 antibody

Background:

Background:

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes

Tsai SC, et al.(2002)J Biol Chem, 277(35): 31826-33

Aliases: D10Wsu179e antibody, HD 2 antibody, HD2 antibody, HDAC 2 antibody, Hdac2 antibody, HDAC2_HUMAN antibody, Histone deacetylase 2 (HD2) antibody, Histone deacetylase 2 antibody, OTTHUMP00000017046 antibody, OTTHUMP00000227077 antibody, OTTHUMP00000227078 antibody, RPD3 antibody, transcriptional regulator homolog RPD3 antibody, YAF1 antibody, YY1 associated factor 1 antibody, YY1 transcription factor binding protein antibody, Yy1bp antibody

UniProt: Q92769

Pathways: Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection