IRAK1 antibody (pSer376)
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- Target See all IRAK1 Antibodies
- IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
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Binding Specificity
- pSer376
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IRAK1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of Serine 376(Q-S-S(p)-M-V) derived from Human IRAK1.
- Isotype
- IgG
- Top Product
- Discover our top product IRAK1 Primary Antibody
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- Application Notes
- IHC:1:50-1:100,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
- Alternative Name
- IRAK1 (IRAK1 Products)
- Synonyms
- IRAK1 antibody, IRAK antibody, pelle antibody, AA408924 antibody, IRAK-1 antibody, IRAK1-S antibody, Il1rak antibody, Plpk antibody, mPLK antibody, RGD1563841 antibody, interleukin 1 receptor associated kinase 1 antibody, interleukin-1 receptor-associated kinase 1 antibody, IRAK1 antibody, irak1 antibody, Irak1 antibody
- Background
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Background:
IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.
Cao Z., Science 271:1128-1131(1996).
Reichwald K., Mamm. Genome 11:182-190(2000).
Jensen L.E., J. Biol. Chem. 276:29037-29044(2001).Aliases: AA48924 antibody, Il1rak antibody, Interleukin 1 receptor associated kinase 1 antibody, Interleukin-1 receptor-associated kinase 1 antibody, IRAK antibody, IRAK-1 antibody, Irak1 antibody, IRAK1-S antibody, IRAK1_HUMAN antibody, mPLK antibody, OTTHUMP00000026014 antibody, OTTHUMP00000026015 antibody, OTTHUMP00000026020 antibody, OTTHUMP00000180621 antibody, Pelle antibody, Pelle homolog antibody, Pelle-like protein kinase antibody, Plpk antibody
- UniProt
- P51617
- Pathways
- NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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