CXCR2 antibody (pSer347)

Catalog No. ABIN7138568

Product Details anti-CXCR2 Antibody

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Binding Specificity: pSer347

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 347(R-P-S(p)-F-V) derived from Human IL-8R beta/CDw128 beta

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CXCR2

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Alternative Name: CXCR2 (CXCR2 Products)

Synonyms: CD182 antibody, CDw128b antibody, CMKAR2 antibody, IL8R2 antibody, IL8RA antibody, IL8RB antibody, CXC-R2 antibody, CXCR-2 antibody, CD128 antibody, CDw128 antibody, Cmkar2 antibody, Gpcr16 antibody, IL-8Rh antibody, IL-8rb antibody, Il8rb antibody, mIL-8RH antibody, C-X-C motif chemokine receptor 2 antibody, chemokine (C-X-C motif) receptor 2 antibody, Cxcr2 antibody, CXCR2 antibody

Background:

Background: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.

Aliases: C-X-C chemokine receptor type 2 antibody, CD 182 antibody, CD182 antibody, CD182 antigen antibody, CDw128b antibody, Chemokine (CXC) receptor 2 antibody, CMKAR2 antibody, CXC-R2 antibody, CXCR 2 antibody, CXCR-2 antibody, CXCR2 antibody, CXCR2_HUMAN antibody, GRO/MGSA receptor antibody, High affinity interleukin-8 receptor B antibody, IL 8 receptor type 2 antibody, IL 8R B antibody, IL-8 receptor type 2 antibody, IL-8R B antibody, IL8 RB antibody, IL8 receptor type 2 antibody, IL8R B antibody, IL8R2 antibody, IL8RA antibody, Interleukin 8 Receptor B antibody, Interleukin 8 receptor, beta antibody, Interleukin 8 receptor, type 2 antibody

UniProt: P25025

Pathways: cAMP Metabolic Process