HNRNPC antibody (pSer260)

Catalog No. ABIN7138520

This Rabbit Polyclonal antibody specifically detects HNRNPC in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for HNRNPC antibody (pSer260) (ABIN7138520)

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HNRNPC Antibody

Binding Specificity: pSer260

Purpose: Phospho-HNRNPC (Ser260) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 260(D-D-S(p)-A-E) derived from Human hnRNP C1/2.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HNRNPC

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Alternative Name: HNRNPC

Background:

Background: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.

Aliases: C1 antibody, C2 antibody, Heterogeneous nuclear ribonucleoprotein C (C1/C2) antibody, Heterogeneous nuclear ribonucleoprotein C antibody, Heterogeneous nuclear ribonucleoproteins C1/C2 antibody, HNRNP antibody, hnRNP C1 / hnRNP C2 antibody, hnRNP C1/C2 antibody, Hnrnpc antibody, HNRPC antibody, HNRPC_HUMAN antibody, MGC104306 antibody, MGC105117 antibody, MGC117353 antibody, MGC131677 antibody, Nuclear ribonucleoprotein particle C1 protein antibody, Nuclear ribonucleoprotein particle C2 protein antibody, SNRPC antibody

UniProt: P07910