HNRNPC antibody (pSer260)

Catalog No. ABIN7138520

Product Details anti-HNRNPC Antibody

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Binding Specificity: pSer260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 260(D-D-S(p)-A-E) derived from Human hnRNP C1/2.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HNRNPC

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Alternative Name: HNRNPC (HNRNPC Products)

Synonyms: C1 antibody, C2 antibody, HNRNP antibody, HNRPC antibody, SNRPC antibody, MGC53243 antibody, HNRNPC antibody, bZ1G18.4 antibody, fb57h12 antibody, fi16b11 antibody, wu:fb57h12 antibody, wu:fi16b11 antibody, zgc:55701 antibody, AL022939 antibody, D14Wsu171e antibody, Hnrpc antibody, Hnrpc1 antibody, Hnrpc2 antibody, hnRNPC1 antibody, hnRNPC2 antibody, hnrnp-C antibody, hnRNP C antibody, hnrnp antibody, hnrpc antibody, snrpc antibody, heterogeneous nuclear ribonucleoprotein C (C1/C2) antibody, heterogeneous nuclear ribonucleoprotein C (C1/C2) S homeolog antibody, heterogeneous nuclear ribonucleoprotein C antibody, heterogeneous nuclear ribonucleoprotein C (C1/C2) L homeolog antibody, HNRNPC antibody, hnrnpc.S antibody, hnrnpc antibody, Hnrnpc antibody, hnrnpc.L antibody

Background:

Background: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.

Aliases: C1 antibody, C2 antibody, Heterogeneous nuclear ribonucleoprotein C (C1/C2) antibody, Heterogeneous nuclear ribonucleoprotein C antibody, Heterogeneous nuclear ribonucleoproteins C1/C2 antibody, HNRNP antibody, hnRNP C1 / hnRNP C2 antibody, hnRNP C1/C2 antibody, Hnrnpc antibody, HNRPC antibody, HNRPC_HUMAN antibody, MGC104306 antibody, MGC105117 antibody, MGC117353 antibody, MGC131677 antibody, Nuclear ribonucleoprotein particle C1 protein antibody, Nuclear ribonucleoprotein particle C2 protein antibody, SNRPC antibody

UniProt: P07910