MELK antibody

Catalog No. ABIN7138308

Product Details anti-MELK Antibody

Target: MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MELK antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around aa.626~630 (I-R-R-Q-R) derived from Human MELK.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MELK

Target: MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))

Alternative Name: MELK (MELK Products)

Synonyms: MELK antibody, xmelk antibody, Melk antibody, HPK38 antibody, AI327312 antibody, MPK38 antibody, mKIAA0175 antibody, fb71b01 antibody, fe01f04 antibody, wu:fb71b01 antibody, wu:fe01f04 antibody, maternal embryonic leucine zipper kinase antibody, maternal embryonic leucine zipper kinase L homeolog antibody, MELK antibody, melk antibody, cgd5_2270 antibody, Melk antibody, melk.L antibody

Background:

Background:

Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.

Seong H.-A., Gil M., Kim K.-T., Kim S.-J., Ha H. Biochem. J. 361:597-604(2002)
Vulsteke V., Beullens M., Boudrez A., Keppens S. Biol. Chem. 279:8642-8647(2004)

Aliases: AI327312 antibody, hMELK antibody, HPK 38 antibody, hPK38 antibody, KIAA0175 antibody, Likely ortholog of maternal embryonic leucine zipper kinase antibody, Maternal embryonic leucine zipper kinase antibody, MELK antibody, MELK_HUMAN antibody, mKIAA0175 antibody, MPK38 antibody, OTTHUMP00000021377 antibody, OTTHUMP00000046113 antibody, pEg3 kinase antibody, Protein kinase Eg3 antibody, Protein kinase PK38 antibody, RP23 382O11.1 antibody, Tyrosine protein kinase MELK antibody

UniProt: Q14680