Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Synaptoporin antibody

SYNPR Reactivity: Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7138150
  • Target See all Synaptoporin (SYNPR) Antibodies
    Synaptoporin (SYNPR)
    Reactivity
    • 24
    • 22
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Rat
    Host
    • 41
    • 3
    Rabbit
    Clonality
    • 44
    Polyclonal
    Conjugate
    • 15
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Synaptoporin antibody is un-conjugated
    Application
    • 38
    • 21
    • 14
    • 13
    • 13
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Cross-Reactivity
    Mouse, Rat
    Purification
    Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    Immunogen
    Peptide sequence around aa.257~261(G-P-T-S-F)derived from Rat synaptophysin 2.
    Isotype
    IgG
    Top Product
    Discover our top product SYNPR Primary Antibody
  • Application Notes
    WB:1:500-1:1000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Synaptoporin (SYNPR)
    Alternative Name
    Synpr (SYNPR Products)
    Synonyms
    si:ch211-263a23.1 antibody, si:zc263a23.1 antibody, wu:fq14d10 antibody, SYNPR antibody, MGC139775 antibody, MGC147520 antibody, DKFZp459F1433 antibody, SPO antibody, 1500003F20Rik antibody, synaptoporin antibody, synpr antibody, SYNPR antibody, Synpr antibody
    Background

    Background:

    Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4).

    Wiedenmann, B. et al. (1986) Proc Natl Acad Sci USA 83, 3500-4.
    Valtorta, F. et al. (2004) Bioessays 26, 445-53.
    Arthur, C.P. and Stowell, M.H. (2007) Structure 15, 707-14.
    Bonanomi, D. et al. (2007) Biochem J 404, 525-34.

    Aliases: Synpr antibody, Synaptoporin antibody

    UniProt
    P22831
You are here:
Support