Synaptotagmin V antibody

Catalog No. ABIN7131272

Product Details anti-Synaptotagmin V Antibody

Target: Synaptotagmin V (SYT5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptotagmin V antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human SYT5

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:15-1:50,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Synaptotagmin V

Target: Synaptotagmin V (SYT5)

Alternative Name: SYT5 (SYT5 Products)

Background:

Background: Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules. May be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca2+-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface.

Aliases: Synaptotagmin 5 antibody, Synaptotagmin IX antibody, Synaptotagmin V antibody, Synaptotagmin-5 antibody, Syt5 antibody, SYT5_HUMAN antibody, SytV antibody

UniProt: O00445

Pathways: Synaptic Vesicle Exocytosis