RNF7 antibody

Catalog No. ABIN7130906

Product Details anti-RNF7 Antibody

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF7 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human RNF7

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:10-1:50,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RNF7

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Alternative Name: RNF7 (RNF7 Products)

Synonyms: CKBBP1 antibody, ROC2 antibody, SAG antibody, Rbx2 antibody, ring finger protein 7 antibody, RNF7 antibody, Rnf7 antibody

Background:

Background: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B).

Aliases: CKBBP 1 antibody, CKBBP1 antibody, CKII beta binding protein 1 antibody, CKII beta-binding protein 1 antibody, Rbx 2 antibody, Rbx2 antibody, RBX2_HUMAN antibody, Regulator of cullins 2 antibody, RING box protein 2 antibody, RING finger protein 7 antibody, RING-box protein 2 antibody, RNF 7 antibody, RNF7 antibody, ROC 2 antibody, ROC2 antibody, SAG antibody, Sensitive to apoptosis gene antibody, Sensitive to apoptosis gene protein antibody, Zinc RING finger protein SAG antibody

UniProt: Q9UBF6

Pathways: Positive Regulation of Endopeptidase Activity