CPT1B antibody (AA 501-600)

Catalog No. ABIN708851

Product Details anti-CPT1B Antibody

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Binding Specificity: AA 501-600

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPT1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody should detect the four Isoforms variants of CPT1B created by alternative splicing.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CPT1B

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CPT1B antibody (ABIN708851)

Huebbe, Dose, Schloesser, Campbell, Glüer, Gupta, Ibrahim, Minihane, Baines, Nebel, Rimbach: "Apolipoprotein E (APOE) genotype regulates body weight and fatty acid utilization- studies in gene targeted replacement mice." in: Molecular nutrition & food research, (2014) (PubMed).

Target Details for CPT1B

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Alternative Name: CPT1B (CPT1B Products)

Synonyms: CPT1-M antibody, CPT1M antibody, CPTI antibody, CPTI-M antibody, M-CPT1 antibody, MCCPT1 antibody, MCPT1 antibody, CPT-IB antibody, M-CPTI antibody, CPT1 antibody, CPTIB antibody, cpt1al antibody, zgc:103709 antibody, CPT1B antibody, MGC147544 antibody, Cpt1 antibody, Cpt1-m antibody, Cpti antibody, Cpti-m antibody, M-cpti antibody, carnitine palmitoyltransferase 1B antibody, carnitine palmitoyltransferase 1B (muscle) antibody, carnitine palmitoyltransferase 1B L homeolog antibody, carnitine palmitoyltransferase 1b, muscle antibody, CPT1B antibody, Cpt1b antibody, cpt1b antibody, cpt1b.L antibody

Background:

Synonyms: Carnitine O-palmitoyltransferase 1, muscle isoform, CPT1-M, Carnitine O-palmitoyltransferase I, muscle isoform, CPT I, CPTI-M, Carnitine palmitoyltransferase 1B, Carnitine palmitoyltransferase I-like protein, CPT1B, KIAA1670

Background: The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009].

Gene ID: 1375

UniProt: Q92523

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process